Implications of Clinical Trial Design on Sample Size Requirements

The primary goal in designing a randomized controlled clinical trial (RCT) is to minimize bias in the estimate of treatment effect. Randomized group assignment, double-blinded assessments, and control or comparison groups reduce the risk of bias. The design must also provide sufficient statistical p...

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Bibliografiset tiedot
Päätekijä: Leon, Andrew C.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Oxford University Press 2008
Aiheet:
Cognitive Neuroscience Treatment to Improve Cognition in Schizophrenia (CNTRICS): Validity, Psychometric, Practicality, and Statistical Issues in Translation
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2632464/
https://ncbi.nlm.nih.gov/pubmed/18469326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/schbul/sbn035
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