Regulatory T Cells Modulate Staphylococcal Enterotoxin B-Induced Effector T-Cell Activation and Acceleration of Colitis

Oral administration of bacterial superantigen Staphylococcus aureus enterotoxin B (SEB) activates mucosal T cells but does not cause mucosal inflammation. We examined the effect of oral SEB on the development of mucosal inflammation in mice in the absence of regulatory T (Treg) cells. SCID mice were...

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Detalhes bibliográficos
Main Authors: Heriazon, Armando, Zhou, Pengfei, Borojevic, Rajka, Foerster, Katharina, Streutker, Catherine J., Ng, Terry, Croitoru, Kenneth
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Host Response and Inflammation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2632032/
https://ncbi.nlm.nih.gov/pubmed/19064639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00822-08
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