Pirfenidone Blocks the In Vitro and In Vivo Effects of Staphylococcal Enterotoxin B
Pirfenidone [5-methyl-1-phenyl-2-(1H)-pyridone] down-regulates expression of cytokines and other mediators involved in the onset and development of pulmonary fibrosis. Pirfenidone also inhibits production of tumor necrosis factor alpha (TNF-α) from macrophages incubated with endotoxin and protects m...
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| Publicado no: | Infect Immun |
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| Principais autores: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology (ASM)
2002
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC127993/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12010989/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.70.6.2989-2994.2002 |
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