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Pirfenidone Blocks the In Vitro and In Vivo Effects of Staphylococcal Enterotoxin B
Pirfenidone [5-methyl-1-phenyl-2-(1H)-pyridone] down-regulates expression of cytokines and other mediators involved in the onset and development of pulmonary fibrosis. Pirfenidone also inhibits production of tumor necrosis factor alpha (TNF-α) from macrophages incubated with endotoxin and protects m...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Microbiology
2002
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC127993/ https://ncbi.nlm.nih.gov/pubmed/12010989 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.70.6.2989-2994.2002 |
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