Humoral Immunity against Capsule Polysaccharide Protects the Host from magA(+) Klebsiella pneumoniae-Induced Lethal Disease by Evading Toll-Like Receptor 4 Signaling

Klebsiella pneumoniae magA (for mucoviscosity-associated gene A) is linked to the pathogenesis of primary pyogenic liver abscess, but the underlying mechanism by which magA increases pathogenicity is not well elucidated. In this study, we investigated the role of the capsular polysaccharides (CPS) i...

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Bibliografiske detaljer
Main Authors: Wu, Ming-Fang, Yang, Chih-Ya, Lin, Tzu-Lung, Wang, Jin-Town, Yang, Feng-Ling, Wu, Shih-Hsiung, Hu, Bor-Shen, Chou, Teh-Ying, Tsai, Ming-Daw, Lin, Chi-Hung, Hsieh, Shie-Liang
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2009
Fag:
Host Response and Inflammation
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2632026/
https://ncbi.nlm.nih.gov/pubmed/19015249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00931-08
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