Humoral Immunity against Capsule Polysaccharide Protects the Host from magA(+) Klebsiella pneumoniae-Induced Lethal Disease by Evading Toll-Like Receptor 4 Signaling

Klebsiella pneumoniae magA (for mucoviscosity-associated gene A) is linked to the pathogenesis of primary pyogenic liver abscess, but the underlying mechanism by which magA increases pathogenicity is not well elucidated. In this study, we investigated the role of the capsular polysaccharides (CPS) i...

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Detalhes bibliográficos
Main Authors: Wu, Ming-Fang, Yang, Chih-Ya, Lin, Tzu-Lung, Wang, Jin-Town, Yang, Feng-Ling, Wu, Shih-Hsiung, Hu, Bor-Shen, Chou, Teh-Ying, Tsai, Ming-Daw, Lin, Chi-Hung, Hsieh, Shie-Liang
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Host Response and Inflammation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2632026/
https://ncbi.nlm.nih.gov/pubmed/19015249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00931-08
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