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Enhanced Immunogenicity of Plasmodium falciparum Peptide Vaccines Using a Topical Adjuvant Containing a Potent Synthetic Toll-Like Receptor 7 Agonist, Imiquimod

Plasmodium sporozoites injected into the skin by malaria-infected mosquitoes can be effectively targeted by antibodies that block parasite invasion of host hepatocytes and thus prevent the subsequent development of blood stage infections responsible for clinical disease. Malaria subunit vaccines req...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Othoro, Caroline, Johnston, Dean, Lee, Rebecca, Soverow, Jonathan, Bystryn, Jean-Claude, Nardin, Elizabeth
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology (ASM) 2009
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2632023/
https://ncbi.nlm.nih.gov/pubmed/19047411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00974-08
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