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Functional Analysis of the Streptomyces coelicolor NrdR ATP-Cone Domain: Role in Nucleotide Binding, Oligomerization, and DNA Interactions

Ribonucleotide reductases (RNRs) are essential enzymes in all living cells, providing the only known de novo pathway for the biosynthesis of deoxyribonucleotides (dNTPs), the immediate precursors of DNA synthesis and repair. RNRs catalyze the controlled reduction of all four ribonucleotides to maint...

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Hlavní autoři: Grinberg, Inna, Shteinberg, Tatyana, Hassan, A. Quamrul, Aharonowitz, Yair, Borovok, Ilya, Cohen, Gerald
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2632000/
https://ncbi.nlm.nih.gov/pubmed/19047342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.01145-08
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