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The Streptomyces NrdR Transcriptional Regulator Is a Zn Ribbon/ATP Cone Protein That Binds to the Promoter Regions of Class Ia and Class II Ribonucleotide Reductase Operons

Ribonucleotide reductases (RNRs) catalyze the conversion of ribonucleotides to deoxyribonucleotides and are essential for de novo DNA synthesis and repair. Streptomyces spp. contain genes coding for two RNRs, either of which is sufficient for vegetative growth. The class Ia RNR is encoded by the nrd...

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Bibliographic Details
Main Authors: Grinberg, Inna, Shteinberg, Tanya, Gorovitz, Batia, Aharonowitz, Yair, Cohen, Gerald, Borovok, Ilya
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2006
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1636249/
https://ncbi.nlm.nih.gov/pubmed/16950922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00903-06
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