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HicA of Escherichia coli Defines a Novel Family of Translation-Independent mRNA Interferases in Bacteria and Archaea

Toxin-antitoxin (TA) loci are common in free-living bacteria and archaea. TA loci encode a stable toxin that is neutralized by a metabolically unstable antitoxin. The antitoxin can be either a protein or an antisense RNA. So far, six different TA gene families, in which the antitoxins are proteins,...

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Main Authors: Jørgensen, Mikkel G., Pandey, Deo P., Jaskolska, Milena, Gerdes, Kenn
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology (ASM) 2009
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2631989/
https://ncbi.nlm.nih.gov/pubmed/19060138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.01013-08
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