Amphetamine and Methamphetamine Differentially Affect Dopamine Transporters in Vitro and in Vivo

The psychostimulants d-amphetamine (AMPH) and methamphetamine (METH) release excess dopamine (DA) into the synaptic clefts of dopaminergic neurons. Abnormal DA release is thought to occur by reverse transport through the DA transporter (DAT), and it is believed to underlie the severe behavioral effe...

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Main Authors: Goodwin, J. Shawn, Larson, Gaynor A., Swant, Jarod, Sen, Namita, Javitch, Jonathan A., Zahniser, Nancy R., De Felice, Louis J., Khoshbouei, Habibeh
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2009
Fag:
Membrane Transport, Structure, Function, and Biogenesis
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2631950/
https://ncbi.nlm.nih.gov/pubmed/19047053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M805298200
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