Amphetamine and Methamphetamine Differentially Affect Dopamine Transporters in Vitro and in Vivo

The psychostimulants d-amphetamine (AMPH) and methamphetamine (METH) release excess dopamine (DA) into the synaptic clefts of dopaminergic neurons. Abnormal DA release is thought to occur by reverse transport through the DA transporter (DAT), and it is believed to underlie the severe behavioral effe...

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Auteurs principaux: Goodwin, J. Shawn, Larson, Gaynor A., Swant, Jarod, Sen, Namita, Javitch, Jonathan A., Zahniser, Nancy R., De Felice, Louis J., Khoshbouei, Habibeh
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2009
Sujets:
Membrane Transport, Structure, Function, and Biogenesis
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2631950/
https://ncbi.nlm.nih.gov/pubmed/19047053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M805298200
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