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Posttranscriptional Regulation of miRNAs Harboring Conserved Terminal Loops
We recently found that hnRNP A1, a protein implicated in many aspects of RNA processing, acts as an auxiliary factor for the Drosha-mediated processing of a microRNA precursor, pri-miR-18a. Here, we provide the mechanism by which hnRNP A1 regulates this event. We show that hnRNP A1 binds to the loop...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cell Press
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2631628/ https://ncbi.nlm.nih.gov/pubmed/18995836 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2008.10.013 |
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