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A basic/hydrophobic cleft of the T4 activator MotA interacts with the C-terminus of E. coli σ(70) to activate middle gene transcription

Transcriptional activation often employs a direct interaction between an activator and RNA polymerase. For activation of its middle genes, bacteriophage T4 appropriates E. coli RNA polymerase through the action of two phage-encoded proteins, MotA and AsiA. Alone, AsiA inhibits transcription from a l...

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Autors principals: Bonocora, Richard P., Caignan, Gregori, Woodrell, Christopher, Werner, Milton H., Hinton, Deborah M.
Format: Artigo
Idioma:Inglês
Publicat: 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2631437/
https://ncbi.nlm.nih.gov/pubmed/18485078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2958.2008.06276.x
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