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A basic/hydrophobic cleft of the T4 activator MotA interacts with the C-terminus of E. coli σ(70) to activate middle gene transcription
Transcriptional activation often employs a direct interaction between an activator and RNA polymerase. For activation of its middle genes, bacteriophage T4 appropriates E. coli RNA polymerase through the action of two phage-encoded proteins, MotA and AsiA. Alone, AsiA inhibits transcription from a l...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2631437/ https://ncbi.nlm.nih.gov/pubmed/18485078 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2958.2008.06276.x |
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