Antibodies and cytokines independently protect against pneumonic plague

Yersinia pestis causes pneumonic plague, an exceptionally virulent disease for which we lack a safe and effective vaccine. Antibodies specific for the Y. pestis F1 and LcrV proteins can protect mice against pulmonary Y. pestis infection. We demonstrate that neutralizing tumor necrosis factor-alpha (...

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Hauptverfasser: Kummer, Lawrence W., Szaba, Frank M., Parent, Michelle A., Adamovicz, Jeffrey J., Hill, Jim, Johnson, Lawrence L., Smiley, Stephen T.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2631396/
https://ncbi.nlm.nih.gov/pubmed/18926869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2008.09.063
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