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Destabilization of the P Site Codon-Anticodon Helix Results from Movement of tRNA into the P/E Hybrid State within the Ribosome
Retention of the reading frame in ribosomal complexes after single-round translocation depends on the acylation state of the tRNA. When tRNA lacking a peptidyl group is translocated to the P site, the mRNA slips to allow re-pairing of the tRNA with a nearby out-of-frame codon. Here, we show that thi...
में बचाया:
| मुख्य लेखकों: | , , , |
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| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
2005
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2631382/ https://ncbi.nlm.nih.gov/pubmed/16307924 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2005.10.007 |
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