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Conditional Deletion of the Retinoblastoma (Rb) Gene in Ovarian Granulosa Cells Leads to Premature Ovarian Failure

The retinoblastoma protein (RB) regulates cell proliferation and survival by binding to the E2F family of transcription factors. Recent studies suggest that RB also regulates differentiation in a variety of cell types, including myocytes, neurons, adipocytes, and chondrocytes. Rb mutations have been...

詳細記述

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書誌詳細
主要な著者: Andreu-Vieyra, Claudia, Chen, Ruihong, Matzuk, Martin M.
フォーマット: Artigo
言語:Inglês
出版事項: The Endocrine Society 2008
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2631371/
https://ncbi.nlm.nih.gov/pubmed/18599617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2008-0033
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