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Inhibition of AP-1 Transcriptional Activity Blocks the Migration, Invasion, and Experimental Metastasis of Murine Osteosarcoma

A well-characterized murine osteosarcoma model for metastasis and invasion was used in this study to determine the role of AP-1 in the progression of this disease. We analyzed K12 and K7M2 cells, two clonally related murine osteosarcoma cell lines that have been characterized as low metastatic or hi...

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Autors principals: Leaner, Virna D., Chick, Jeffrey F., Donninger, Howard, Linniola, Ilona, Mendoza, Arnulfo, Khanna, Chand, Birrer, Michael J.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Investigative Pathology 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2631339/
https://ncbi.nlm.nih.gov/pubmed/19074613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2009.071006
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