p47(phox) Deficiency Induces Macrophage Dysfunction Resulting in Progressive Crystalline Macrophage Pneumonia

Nicotinamide dinucleotide phosphate oxidase-deficient (p47(phox−/−)) mice are a model of human chronic granulomatous disease; these mice are prone to develop systemic infections and inflammatory diseases. The use of antibiotic (Bactrim) prophylaxis in a specific pathogen-free environment, however, i...

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Autors principals: Liu, Qi, Cheng, Lily I., Yi, Liang, Zhu, Nannan, Wood, Adam, Changpriroa, Cattlena May, Ward, Jerrold M., Jackson, Sharon H.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Investigative Pathology 2009
Matèries:
Regular Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2631328/
https://ncbi.nlm.nih.gov/pubmed/19095958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2009.080555
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