Latent Transforming Growth Factor-β-Binding Protein-4 Regulates Transforming Growth Factor-β1 Bioavailability for Activation by Fibrogenic Lung Fibroblasts in Response to Bleomycin

Recent evidence suggests that subsets of lung fibroblasts differentially contribute to fibrogenic progression. We have previously shown that a subset of rat lung fibroblasts with fibrogenic characteristics [Thy-1 (−) fibroblasts] responds to stimuli (bleomycin, interleukin-4, etc) with increased lat...

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Main Authors: Zhou, Yong, Koli, Katri, Hagood, James S., Miao, Mi, Mavalli, Mahendra, Rifkin, Daniel B., Murphy-Ullrich, Joanne E.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Investigative Pathology 2009
Assuntos:
Regular Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2631315/
https://ncbi.nlm.nih.gov/pubmed/19056849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2009.080620
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