PKCα regulates platelet granule secretion and thrombus formation in mice

Platelets are central players in atherothrombosis development in coronary artery disease. The PKC family provides important intracellular mechanisms for regulating platelet activity, and platelets express several members of this family, including the classical isoforms PKCα and PKCβ and novel isofor...

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Détails bibliographiques
Auteurs principaux: Konopatskaya, Olga, Gilio, Karen, Harper, Matthew T., Zhao, Yan, Cosemans, Judith M.E.M., Karim, Zubair A., Whiteheart, Sidney W., Molkentin, Jeffery D., Verkade, Paul, Watson, Steve P., Heemskerk, Johan W.M., Poole, Alastair W.
Format: Artigo
Langue:Inglês
Publié: American Society for Clinical Investigation 2009
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2631290/
https://ncbi.nlm.nih.gov/pubmed/19147982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI34665
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