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Cross-strand split tetra-Cys motifs as structure sensors in a β-sheet protein
We have designed ‘split tetra-Cys motifs’ that bind the biarsenical fluorescein dye FlAsH across strands of a model β-rich protein. Our strategy was to divide the linear FlAsH-binding tetra-Cys sequence such that dye could be fully liganded only when the strands were arranged in space correctly by n...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2631173/ https://ncbi.nlm.nih.gov/pubmed/18940670 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2008.09.006 |
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