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Boosting BCG vaccination with MVA85A down-regulates the immunoregulatory cytokine TGF-β1
In clinical trials recombinant-modified vaccinia virus Ankara expressing the Mycobacterium tuberculosis antigen 85A (MVA85A) induces approximately 10 times more effector T cells than any other recombinant MVA vaccine. We have found that in BCG primed subjects MVA85A vaccination reduces transforming...
Bewaard in:
Hoofdauteurs: | , , , , , , , , |
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Formaat: | Artigo |
Taal: | Inglês |
Gepubliceerd in: |
Elsevier Science
2008
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Onderwerpen: | |
Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2631167/ https://ncbi.nlm.nih.gov/pubmed/18682270 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2008.07.040 |
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