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Design of 240,000 orthogonal 25mer DNA barcode probes

DNA barcodes linked to genetic features greatly facilitate screening these features in pooled formats using microarray hybridization, and new tools are needed to design large sets of barcodes to allow construction of large barcoded mammalian libraries such as shRNA libraries. Here we report a framew...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Xu, Qikai, Schlabach, Michael R., Hannon, Gregory J., Elledge, Stephen J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2631075/
https://ncbi.nlm.nih.gov/pubmed/19171886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0812506106
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