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Identification of two distinct structural regions in a human porcine endogenous retrovirus receptor, HuPAR2, contributing to function for viral entry

BACKGROUND: Of the three subclasses of Porcine Endogenous Retrovirus (PERV), PERV-A is able to infect human cells via one of two receptors, HuPAR1 or HuPAR2. Characterizing the structure-function relationships of the two HuPAR receptors in PERV-A binding and entry is important in understanding recep...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Marcucci, Katherine T, Argaw, Takele, Wilson, Carolyn A, Salomon, Daniel R
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2630988/
https://ncbi.nlm.nih.gov/pubmed/19144196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-6-3
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