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Detailed Mapping of Determinants within the Porcine Endogenous Retrovirus Envelope Surface Unit Identifies Critical Residues for Human Cell Infection within the Proline-Rich Region

Replication-competent porcine endogenous retroviruses (PERVs) are either human cell tropic (PERV-A and PERV-B) or non-human cell tropic (PERV-C). We previously demonstrated that PERV in vitro cell tropism is modulated by 2 residues within the C terminus of SU and that the PERV receptor binding domai...

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Detalhes bibliográficos
Main Authors: Argaw, Takele, Wilson, Carolyn A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3416145/
https://ncbi.nlm.nih.gov/pubmed/22696659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00738-12
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