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Activity of Levofloxacin Alone and in Combination with a DnaK Inhibitor against Gram-Negative Rods, Including Levofloxacin-Resistant Strains

Synergy time-kill testing of levofloxacin alone and in combination with CHP-105, a representative DnaK inhibitor, against 50 gram-negative rods demonstrated that 34 of the 50 strains tested showed significant synergy between levofloxacin and CHP-105 after 12 h and 24 h. Fourteen of these 34 organism...

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Hlavní autoři: Credito, Kim, Lin, Gengrong, Koeth, Laura, Sturgess, Michael A., Appelbaum, Peter C.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2630640/
https://ncbi.nlm.nih.gov/pubmed/19015359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01132-08
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