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Activity of Daptomycin Alone and in Combination with Rifampin and Gentamicin against Staphylococcus aureus Assessed by Time-Kill Methodology

The synergistic effects of daptomycin plus gentamicin or rifampin were tested against 50 Staphylococcus aureus strains, with daptomycin MICs ranging between 0.25 and 8 μg/ml. Daptomycin sub-MICs combined with gentamicin concentrations lower than the MIC yielded synergy in 34 (68%) of the 50 strains....

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Main Authors: Credito, Kim, Lin, Gengrong, Appelbaum, Peter C.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2007
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1855505/
https://ncbi.nlm.nih.gov/pubmed/17220402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01455-06
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