Compounds Structurally Related to Ellagic Acid Show Improved Antiplasmodial Activity

The cancer chemopreventive agent ellagic acid (EA) is a known inhibitor of glutathione S-transferases (GSTs) and possesses antiplasmodial activities in the upper-nanomolar range. In the recent drug development approach, the properties of the active site of Plasmodium falciparum GST were exploited fo...

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Bibliographic Details
Main Authors: Sturm, Nicole, Hu, Ying, Zimmermann, Herbert, Fritz-Wolf, Karin, Wittlin, Sergio, Rahlfs, Stefan, Becker, Katja
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2009
Subjects:
Experimental Therapeutics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2630624/
https://ncbi.nlm.nih.gov/pubmed/19015351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00544-08
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