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Plasmodium falciparum glutathione S-transferase—Structural and mechanistic studies on ligand binding and enzyme inhibition

Glutathione S-transferase of the malarial parasite Plasmodium falciparum (PfGST) represents a novel class of GST isoenzymes. Since the architecture of the PfGST substrate binding site differs significantly from its human counterparts and there is only this one isoenzyme present in the parasite, PfGS...

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Bibliografiske detaljer
Main Authors: Hiller, Nicole, Fritz-Wolf, Karin, Deponte, Marcel, Wende, Wolfgang, Zimmermann, Herbert, Becker, Katja
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory Press 2006
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2242455/
https://ncbi.nlm.nih.gov/pubmed/16385005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.051891106
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