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Plasmodium falciparum glutathione S-transferase—Structural and mechanistic studies on ligand binding and enzyme inhibition

Glutathione S-transferase of the malarial parasite Plasmodium falciparum (PfGST) represents a novel class of GST isoenzymes. Since the architecture of the PfGST substrate binding site differs significantly from its human counterparts and there is only this one isoenzyme present in the parasite, PfGS...

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Detalhes bibliográficos
Main Authors: Hiller, Nicole, Fritz-Wolf, Karin, Deponte, Marcel, Wende, Wolfgang, Zimmermann, Herbert, Becker, Katja
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2242455/
https://ncbi.nlm.nih.gov/pubmed/16385005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.051891106
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