T-Cell Activation Leads to Reduced Collagen Maturation in Atherosclerotic Plaques of Apoe(−/−) Mice

Rupture of the collagenous, fibrous cap of an atherosclerotic plaque commonly causes thrombosis. Activated immune cells can secrete mediators that jeopardize the integrity of the fibrous cap. This study aimed to determine the relationship between T-cell-mediated inflammation and collagen turnover in...

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Главные авторы: Ovchinnikova, Olga, Robertson, Anna-Karin L., Wågsäter, Dick, Folco, Eduardo J., Hyry, Marjo, Myllyharju, Johanna, Eriksson, Per, Libby, Peter, Hansson, Göran K.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Investigative Pathology 2009
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Regular Articles
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2630576/
https://ncbi.nlm.nih.gov/pubmed/19131590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2009.080561
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