T-Cell Activation Leads to Reduced Collagen Maturation in Atherosclerotic Plaques of Apoe(−/−) Mice

Rupture of the collagenous, fibrous cap of an atherosclerotic plaque commonly causes thrombosis. Activated immune cells can secrete mediators that jeopardize the integrity of the fibrous cap. This study aimed to determine the relationship between T-cell-mediated inflammation and collagen turnover in...

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Hlavní autoři: Ovchinnikova, Olga, Robertson, Anna-Karin L., Wågsäter, Dick, Folco, Eduardo J., Hyry, Marjo, Myllyharju, Johanna, Eriksson, Per, Libby, Peter, Hansson, Göran K.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Investigative Pathology 2009
Témata:
Regular Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2630576/
https://ncbi.nlm.nih.gov/pubmed/19131590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2009.080561
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