FoxP3(+) Regulatory T Cells Suppress Early Stages of Granuloma Formation but Have Little Impact on Sarcoidosis Lesions

Sarcoidosis is characterized by a disproportionate Th1 granulomatous immune response in involved organs. It is also associated with both peripheral and intratissular regulatory T cell (Treg) expansion. These cells exhibit powerful antiproliferative activity, yet do not completely inhibit the product...

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Detalhes bibliográficos
Main Authors: Taflin, Cécile, Miyara, Makoto, Nochy, Dominique, Valeyre, Dominique, Naccache, Jean-Marc, Altare, Frédéric, Salek-Peyron, Pascale, Badoual, Cécile, Bruneval, Patrick, Haroche, Julien, Mathian, Alexis, Amoura, Zahir, Hill, Gary, Gorochov, Guy
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2009
Assuntos:
Regular Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2630558/
https://ncbi.nlm.nih.gov/pubmed/19147826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2009.080580
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