Sialyl Lewis x (CD15s) identifies highly differentiated and most suppressive FOXP3(high) regulatory T cells in humans

CD4(+) regulatory T (Treg) cells expressing CD25 and the transcription factor forkhead box P3 (FOXP3) are indispensable for immunological self-tolerance and homeostasis. FOXP3(+)CD25(+)CD4(+) T cells in humans, however, are heterogeneous in function and differentiation status, including suppressive...

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Bibliografske podrobnosti
izdano v:Proc Natl Acad Sci U S A
Main Authors: Miyara, Makoto, Chader, Driss, Sage, Edouard, Sugiyama, Daisuke, Nishikawa, Hiroyoshi, Bouvry, Diane, Claër, Laetitia, Hingorani, Ravi, Balderas, Robert, Rohrer, Jurg, Warner, Noel, Chapelier, Alain, Valeyre, Dominique, Kannagi, Reiji, Sakaguchi, Shimon, Amoura, Zahir, Gorochov, Guy
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2015
Teme:
Biological Sciences
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4466753/
https://ncbi.nlm.nih.gov/pubmed/26015572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1508224112
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