Plasminogen Activator Inhibitor-1 Protects Endothelial Cells from FasL-Mediated Apoptosis

Plasminogen activator inhibitor-1 (PAI-1) paradoxically enhances tumor progression and angiogenesis, however the mechanism supporting this role is not known. Here we provide evidence that PAI-1 is essential to protect endothelial cells (EC) from FasL-mediated apoptosis. In the absence of host-derive...

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Hlavní autoři: Bajou, Khalid, Peng, Hongjun, Laug, Walter E., Maillard, Catherine, Noel, Agnes, Foidart, Jean M., Martial, Joseph A., DeClerck, Yves A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2630529/
https://ncbi.nlm.nih.gov/pubmed/18835034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccr.2008.08.012
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