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Genetically modified adenoviral vector with the protein transduction domain of Tat improves gene transfer to CAR-deficient cells
The transduction efficiency of Ad (adenovirus) depends, to some extent, on the expression level of CAR (coxsackievirus and Ad receptor) of a target cell. The low level of CAR on the cell surface is a potential barrier to efficient gene transfer. To overcome this problem, PTD.AdeGFP (where eGFP is en...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Portland Press Ltd.
2009
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2630516/ https://ncbi.nlm.nih.gov/pubmed/18721127 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BSR20080023 |
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