Genetically modified adenoviral vector with the protein transduction domain of Tat improves gene transfer to CAR-deficient cells

The transduction efficiency of Ad (adenovirus) depends, to some extent, on the expression level of CAR (coxsackievirus and Ad receptor) of a target cell. The low level of CAR on the cell surface is a potential barrier to efficient gene transfer. To overcome this problem, PTD.AdeGFP (where eGFP is en...

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Hlavní autoři: Liu, Shihai, Mao, Qinwen, Zhang, Weifeng, Zheng, Xiaojing, Bian, Ye, Wang, Dongyang, Li, Huijin, Chai, Lihong, Zhao, Junli, Xia, Haibin
Médium: Artigo
Jazyk:Inglês
Vydáno: Portland Press Ltd. 2009
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Original Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2630516/
https://ncbi.nlm.nih.gov/pubmed/18721127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BSR20080023
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