State-dependent cAMP sensitivity of presynaptic function underlies metaplasticity in a hippocampal feedforward inhibitory circuit

At hippocampal mossy fiber (MF)-st. lucidum interneuron (SLIN) synapses mGluR7 serves as a metaplastic switch controlling bidirectional plasticity. mGluR7 activation during high-frequency stimulation (HFS) triggers presynaptic LTD due to persistent P/Q-type Ca(2+) channel inhibition. However, follow...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Pelkey, Kenneth A., Topolnik, Lisa, Yuan, Xiao-Qing, Lacaille, Jean-Claude, McBain, Chris J.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2008
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2630456/
https://ncbi.nlm.nih.gov/pubmed/19109906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2008.11.018
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