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State-dependent cAMP sensitivity of presynaptic function underlies metaplasticity in a hippocampal feedforward inhibitory circuit
At hippocampal mossy fiber (MF)-st. lucidum interneuron (SLIN) synapses mGluR7 serves as a metaplastic switch controlling bidirectional plasticity. mGluR7 activation during high-frequency stimulation (HFS) triggers presynaptic LTD due to persistent P/Q-type Ca(2+) channel inhibition. However, follow...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2630456/ https://ncbi.nlm.nih.gov/pubmed/19109906 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2008.11.018 |
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