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Interleukin(IL)-1 Regulates Ozone-enhanced Tracheal Smooth Muscle Responsiveness by Increasing Substance P (SP) Production in Intrinsic Airway Neurons of Ferret

Exposure to ozone induces airway hyperresponsiveness (AHR) mediated partly by SP released from nerve terminals of intrinsic airway neurons. Our recent studies showed that IL-1, an important multifunctional proinflammatory cytokine, increases synthesis and release of SP from intrinsic airway neurons....

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Main Authors: Wu, Z.-X., Barker, J. S., Batchelor, T. P., Dey, R.D.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2008
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2630406/
https://ncbi.nlm.nih.gov/pubmed/18718561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.resp.2008.07.019
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