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In Vitro and in Vivo Pharmacological Characterization of the Neuropeptide S Receptor Antagonist [d-Cys(tBu)(5)]Neuropeptide S
Neuropeptide S (NPS) was identified as the endogenous ligand of an orphan receptor now referred to as the NPS receptor (NPSR). In the frame of a structure-activity study performed on NPS Gly5, the NPSR ligand [d-Cys(tBu)(5)]NPS was identified. [d-Cys(tBu)(5)]NPS up to 100 μM did not stimulate calciu...
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| Main Authors: | , , , , , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
American Society for Pharmacology and Experimental Therapeutics
2009
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2630366/ https://ncbi.nlm.nih.gov/pubmed/18971372 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.108.143867 |
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