IL-12 Enhances CTL Synapse Formation and Induces Self-reactivity

Immunological synapse formation between T cells and target cells can affect the functional outcome of TCR ligation by a given MHC/peptide complex. Although synapse formation is usually induced by TCR signaling, it is not clear whether other factors can affect the efficiency of synapse formation. Her...

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Bibliografiske detaljer
Main Authors: Markiewicz, Mary A., Wise, Erica L., Buchwald, Zachary S., Cheney, Elizabeth E., Hansen, Ted H., Suri, Anish, Cemerski, Saso, Allen, Paul M., Shaw, Andrey S.
Format: Artigo
Sprog:Inglês
Udgivet: 2009
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2630174/
https://ncbi.nlm.nih.gov/pubmed/19155481
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