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Insulin Enhances Nitric Oxide Production in Trabecular Meshwork Cells via De Novo Pathway for Tetrahydrobiopterin Synthesis

PURPOSE: To investigate the effect of insulin on the production of nitric oxide (NO) in the trabecular meshwork (TM) cells and the enzymatic synthetic pathway of tetrahydrobiopterin (BH(4)) synthesis. METHODS: Primarily cultured human TM cells were exposed to 1, 10, and 100 µg/ml of insulin and 0, 1...

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Detalles Bibliográficos
Autor Principal: Kim, Jae Woo
Formato: Artigo
Idioma:Inglês
Publicado: The Korean Ophthalmological Society 2007
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2629692/
https://ncbi.nlm.nih.gov/pubmed/17460431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3341/kjo.2007.21.1.39
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