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Insulin Enhances Nitric Oxide Production in Trabecular Meshwork Cells via De Novo Pathway for Tetrahydrobiopterin Synthesis
PURPOSE: To investigate the effect of insulin on the production of nitric oxide (NO) in the trabecular meshwork (TM) cells and the enzymatic synthetic pathway of tetrahydrobiopterin (BH(4)) synthesis. METHODS: Primarily cultured human TM cells were exposed to 1, 10, and 100 µg/ml of insulin and 0, 1...
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| Главный автор: | |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
The Korean Ophthalmological Society
2007
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2629692/ https://ncbi.nlm.nih.gov/pubmed/17460431 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3341/kjo.2007.21.1.39 |
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