COX2 (PTGS2) gene methylation in epithelial, subepithelial lymphocyte and stromal tissue compartments in a spectrum of esophageal squamous neoplasia

BACKGROUND: Previous studies have shown important effects of stromal elements in carcinogenesis. To explore the tumor-stromal relationship in esophageal neoplasia, we examined methylation of COX-2 (PTGS2), a gene etiologically associated with the development of gastrointestinal cancers, in adjacent...

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Hauptverfasser: Dawsey, Sonja P., Roth, Mark J., Adams, Lisa, Hu, Nan, Wang, Quan-Hong, Taylor, Philip R., Woodson, Karen
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2629649/
https://ncbi.nlm.nih.gov/pubmed/18632220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cdp.2008.05.001
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