Effect of Variation in CHI3L1 on Serum YKL-40 Level, Risk of Asthma, and Lung Function

BACKGROUND: The chitinase-like protein YKL-40 is involved in inflammation and tissue remodeling. We recently showed that serum YKL-40 levels were elevated in patients with asthma and were correlated with severity, thickening of the subepithelial basement membrane, and pulmonary function. We hypothes...

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Detalhes bibliográficos
Main Authors: Ober, Carole, Tan, Zheng, Sun, Ying, Possick, Jennifer D., Pan, Lin, Nicolae, Raluca, Radford, Sadie, Parry, Rodney R., Heinzmann, Andrea, Deichmann, Klaus A., Lester, Lucille A., Gern, James E., Lemanske, Robert F., Nicolae, Dan L., Elias, Jack A., Chupp, Geoffrey L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2629486/
https://ncbi.nlm.nih.gov/pubmed/18403759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1056/NEJMoa0708801
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