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Long-chain carboxychromanols, metabolites of vitamin E, are potent inhibitors of cyclooxygenases
Cyclooxygenase (COX-1/COX-2)-catalyzed eicosanoid formation plays a key role in inflammation-associated diseases. Natural forms of vitamin E are recently shown to be metabolized to long-chain carboxychromanols and their sulfated counterparts. Here we find that vitamin E forms differentially inhibit...
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| Autori principali: | , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
2008
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2629323/ https://ncbi.nlm.nih.gov/pubmed/19074288 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0810962106 |
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