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Severe growth retardation and early lethality in mice lacking the nuclear localization sequence and C-terminus of PTH-related protein

Parathyroid hormone (PTH) plays a central role in the regulation of serum calcium and phosphorus homeostasis, while parathyroid hormone-related protein (PTHrP) has important developmental roles. Both peptides signal through the same G protein-coupled receptor, the PTH/PTHrP or PTH type 1 receptor (P...

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Bibliografski detalji
Glavni autori: Miao, Dengshun, Su, Hanyi, He, Bin, Gao, Jianjun, Xia, Qingwen, Zhu, Min, Gu, Zhen, Goltzman, David, Karaplis, Andrew C.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2008
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2629292/
https://ncbi.nlm.nih.gov/pubmed/19091948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0805690105
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